<p style="font-family: arial,helvetica,sans-serif;" class="MsoNormal"><span style="font-size: 10pt; line-height: 115%;">Dear
</span><span style="font-size: 10pt; line-height: 115%;">Carsten
and David and </span><span style="font-size: 10pt; line-height: 115%;">Tsjerk</span></p><p style="font-family: arial,helvetica,sans-serif;" class="MsoNormal"><span style="font-size: 10pt; line-height: 115%;"><br></span></p>
<p style="font-family: arial,helvetica,sans-serif;" class="MsoNormal"><span style="font-size: 10pt; line-height: 115%;">Thanks
for your time and attention</span></p><p style="font-family: arial,helvetica,sans-serif;" class="MsoNormal"><span style="font-size: 10pt; line-height: 115%;"><br></span></p>
<p style="font-family: arial,helvetica,sans-serif;" class="MsoNormal"><span style="font-size: 10pt; line-height: 115%;">My
purpose of these questions is to find a way that 1) close two separated strand
of dna (in my case only –pbc nojump fix it) and also 2) water molecules to be put
in interface of between protein and dna. Because I want to survey interfacial
water molecules and dynamics of water mediated hydrogen bonds. </span><span style="font-size: 10pt; line-height: 115%;"></span></p>