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</o:shapelayout></xml><![endif]--></head><body lang=ZH-CN link=blue vlink=purple style='text-justify-trim:punctuation'><div class=WordSection1><p class=MsoNormal><span lang=EN-US style='font-size:12.0pt;font-family:"Cambria","serif"'>Dear Justin A. Lemkul:<o:p></o:p></span></p><p class=MsoNormal><span lang=EN-US style='font-size:12.0pt;font-family:"Cambria","serif"'> Thanks for your rapid reply.<o:p></o:p></span></p><p class=MsoNormal><span lang=EN-US style='font-size:12.0pt;font-family:"Cambria","serif"'> Just as you said, the result of my simulation with different xy p_ref values didn’t vary, they are almost the same.<o:p></o:p></span></p><p class=MsoNormal><span lang=EN-US style='font-size:12.0pt;font-family:"Cambria","serif"'> I think I need consider some other ways to do what I was mean to do.<o:p></o:p></span></p><p class=MsoNormal><span lang=EN-US style='font-size:12.0pt;font-family:"Cambria","serif"'> <o:p></o:p></span></p><p class=MsoNormal style='text-indent:21.0pt'><span lang=EN-US style='font-size:12.0pt;font-family:"Cambria","serif"'>I have read a paper that study the different lateral pressure profiles of lipid membrane with respect to sterol type, I think I may chose this as a way to produce different pressure profiles.<o:p></o:p></span></p><p class=MsoNormal style='text-indent:21.0pt'><span lang=EN-US style='font-size:12.0pt;font-family:"Cambria","serif"'><o:p> </o:p></span></p><p class=MsoNormal><i><span lang=EN-US style='font-size:11.0pt;font-family:"Cambria","serif"'>Ollila, O. H. S., T. Rog, et al. (2007). "Role of sterol type on lateral pressure profiles of lipid membranes affecting membrane protein functionality: Comparison between cholesterol, desmosterol, 7-dehydrocholesterol and ketosterol." <u>Journal of Structural Biology</u> <b>159</b>(2): 311-323.<o:p></o:p></span></i></p><p class=MsoNormal><span lang=EN-US style='font-size:12.0pt;font-family:"Cambria","serif"'><o:p> </o:p></span></p><p class=MsoNormal><span lang=EN-US style='font-size:12.0pt;font-family:"Cambria","serif"'>And, what’s more, Do you think steered MD is a choice?<o:p></o:p></span></p><p class=MsoNormal><span lang=EN-US style='font-size:12.0pt;font-family:"Cambria","serif"'><o:p> </o:p></span></p><p class=MsoNormal><span lang=EN-US style='font-size:12.0pt;font-family:"Cambria","serif"'>KONG Xian<o:p></o:p></span></p></div> <BR><BR>__________ Information from ESET NOD32 Antivirus, version of virus signature database 6327 (20110726) __________<BR><BR>The message was checked by ESET NOD32 Antivirus.<BR><BR><A HREF="http://www.eset.com">http://www.eset.com</A><BR> </body></html>