<html><head></head><body style="word-wrap: break-word; -webkit-nbsp-mode: space; -webkit-line-break: after-white-space; ">Hi Chris and Justin,<div><br></div><div><div><div>On 18/08/2011, at 9:36 AM, Justin A. Lemkul wrote:</div><br class="Apple-interchange-newline"><blockquote type="cite"><div><br><br><a href="mailto:chris.neale@utoronto.ca">chris.neale@utoronto.ca</a> wrote:<br><blockquote type="cite">You'll need to provide a much better report than this if you want to receive any useful help.<br></blockquote><blockquote type="cite">Copy and paste the exact commands of what you did<br></blockquote><blockquote type="cite">Copy and paste the exact log file and error messages<br></blockquote><br></div></blockquote><div><br></div><div>The command I had used (for both 4.0.7 and 4.5.4) are:</div><div><br></div><div><font class="Apple-style-span" face="'Courier New'">pdb2gmx -f 1EXR.pdb -o 1EXR.gro -water spc -ignh -p 1EXR.top -i 1EXR.itp<br>editconf -f 1EXR.gro -o 1EXR_box.gro -c -d 1.4 -bt cubic<br><br>genbox -cp 1EXR_box.gro -cs spc216.gro -o 1EXR_solv.gro -p 1EXR.top -seed 5<br><br>grompp -f em.mdp -c 1EXR_solv.gro -p 1EXR.top -o ions.tpr<br>genion -s ions.tpr -o 1EXR_solv_ions.gro -p 1EXR.top -pname NA+ -nname CL- -np 17 -seed 66</font></div><div><font class="Apple-style-span" face="'Courier New'"><br></font></div><div><font class="Apple-style-span" face="'Courier New'">grompp -f em.mdp -c 1EXR_solv_ions.gro -p 1EXR.top -o em.tpr<br><br>mpirun mdrun_d_mpi -v -s em.tpr -x 1EXR_em.xtc -e 1EXR_em.edr -g 1EXR_em.log -c 1EXR_em.gro<br><br>grompp -f pr.mdp -c 1EXR_em.gro -p 1EXR.top -o pr.tpr<br><br>mpirun mdrun_d_mpi -v -stepout 1000 -s pr.tpr -x 1EXR_pr.xtc -e 1EXR_pr.edr -g 1EXR_pr.log -o 1EXR_pr.trr -c 1EXR_pr.gro<br><br>grompp -f md_start.mdp -c 1EXR_pr.gro -p 1EXR.top -o md.tpr<br><br>mpirun mdrun_d_mpi -v -stepout 10000 -s md.tpr -x 1EXR_md.xtc -e 1EXR_md.edr -g 1EXR_md.log -o 1EXR_md.trr -c 1EXR_md.gro </font><br><br></div><div>The em.mdp:</div><div>i<font class="Apple-style-span" face="'Courier New'">ntegrator = steep<br>maximum number of steps to integrate<br>nsteps<span class="Apple-tab-span" style="white-space:pre"> </span> = 50000<br>;Energy minimizing stuff<br>emstep = 0.001<br>emtol = 100.0<br><br>; OPTIONS FOR BONDS<br>constraints = none<br><br><br>; OUTPUT CONTROL OPTIONS<br>; Output frequency for coords (x), velocities (v) and forces (f)<br>nstxout = 1000<br>nstvout = 1000<br>nstfout = 1000<br>; Output frequency and precision for xtc file<br>nstxtcout = 1000<br>xtc-precision = 1000<br>; Energy monitoring<br>energygrps = system<br><br>; NEIGHBORSEARCHING PARAMETERS<br>; nblist update frequency<br>nstlist = 5 <br>; ns algorithm (simple or grid)<br>ns-type = Grid<br>; nblist cut-off <br>rlist = 0.8<br><br>; OPTIONS FOR ELECTROSTATICS AND VDW<br>; Method for doing electrostatics<br>coulombtype = Reaction-Field<br>rcoulomb = 1.4<br>; Dielectric constant (DC) for cut-off or DC of reaction field<br>epsilon-rf = 62<br>; Method for doing Van der Waals<br>vdw-type = Cut-off<br>; cut-off lengths <br>rvdw = 1.4<br>; Apply long range dispersion corrections for Energy and Pressure<br>DispCorr = No<br><br>; Center of mass control<br>nstcomm = 1000<br>; Periodic boundary conditions <br>pbc = xyz<br>; Mode for center of mass motion removal<br>comm-mode = linear<br>; Groups for center of mass motion removal<br>comm-grps = system</font><br><br></div><div>the pr.mdp:</div><div><font class="Apple-style-span" face="'Courier New'">define <span class="Apple-tab-span" style="white-space:pre"> </span> = -DPOSRES<br><br>integrator <span class="Apple-tab-span" style="white-space:pre"> </span> = md<br>dt <span class="Apple-tab-span" style="white-space:pre"> </span> = 0.002<span class="Apple-tab-span" style="white-space:pre"> </span>; ps !<br>nsteps <span class="Apple-tab-span" style="white-space:pre"> </span> = 50000<span class="Apple-tab-span" style="white-space:pre"> </span>; total 100ps.<br><br>; OPTIONS FOR BONDS<br>; Constrain control<br>constraints<span class="Apple-tab-span" style="white-space:pre"> </span> = all-bonds<br>; Do not constrain the start configuration<br>continuation = no<br>; Type of constraint algorithm<br>constraint-algorithm = lincs<br><br>; OUTPUT CONTROL OPTIONS<br>; Output frequency for coords (x), velocities (v) and forces (f)<br>nstxout = 100000<br>nstvout <span class="Apple-tab-span" style="white-space:pre"> </span> = 100000<br>nstfout <span class="Apple-tab-span" style="white-space:pre"> </span> = 100000<br>; Output frequency and precision for xtc file<br>nstxtcout <span class="Apple-tab-span" style="white-space:pre"> </span> = 5000<br>xtc-precision <span class="Apple-tab-span" style="white-space:pre"> </span> = 1000<br>; Energy monitoring<br>energygrps <span class="Apple-tab-span" style="white-space:pre"> </span> = Protein<span class="Apple-tab-span" style="white-space:pre"> </span>Non-protein<span class="Apple-tab-span" style="white-space:pre"> </span><br>nstenergy<span class="Apple-tab-span" style="white-space:pre"> </span> = 5000<br><br>; NEIGHBORSEARCHING PARAMETERS<br>; nblist update frequency<br>nstlist <span class="Apple-tab-span" style="white-space:pre"> </span> = 5 <br>; ns algorithm (simple or grid)<br>ns-type <span class="Apple-tab-span" style="white-space:pre"> </span> = Grid<br>; nblist cut-off <br>rlist <span class="Apple-tab-span" style="white-space:pre"> </span> = 0.8<br><br>; OPTIONS FOR ELECTROSTATICS AND VDW<br>; Method for doing electrostatics<br>coulombtype = Reaction-Field <br>rcoulomb <span class="Apple-tab-span" style="white-space:pre"> </span> = 1.4 <br>epsilon_rf<span class="Apple-tab-span" style="white-space:pre"> </span> = 62 ; As suggested at J Comput Chem. 2004 Oct;25(13):1656-76.<br>vdw-type = Cut-off<br>; cut-off lengths <br>rvdw = 1.4<br>; Apply long range dispersion corrections for Energy and Pressure<br>DispCorr = no<br><br>; OPTIONS FOR WEAK COUPLING ALGORITHMS<br>; Temperature coupling <br>tcoupl = berendsen<br>; Groups to couple separately, time constant (ps) and reference temperature (K)<br>tc-grps = Protein Non-Protein<br>tau-t = 0.1<span class="Apple-tab-span" style="white-space:pre"> </span> 0.1<br>ref-t = 300<span class="Apple-tab-span" style="white-space:pre"> </span> 300<br>; Pressure coupling <br>Pcoupl = berendsen<br>Pcoupltype = isotropic<br>; Time constant (ps), compressibility (1/bar) and reference P (bar)<br>tau_p = 1.0 <br>compressibility = 4.5e-5 <br>ref_p = 1.0<br>; Generate velocites is on at 290K - do not get velocity from gro file.<br>gen_vel = yes<br>gen_temp = 290<br>gen-seed = -1<br><br><br><br>; Center of mass control<br>nstcomm = 1000<br>; Periodic boundary conditions <br>pbc = xyz<br>; Mode for center of mass motion removal<br>comm-mode = Linear<br>; Groups for center of mass motion removal<br>comm-grps = system</font><br><br></div><div>and the md.mdp:</div><div><font class="Apple-style-span" face="'Courier New'">integrator <span class="Apple-tab-span" style="white-space:pre"> </span> = md<br>dt <span class="Apple-tab-span" style="white-space:pre"> </span> = 0.002<span class="Apple-tab-span" style="white-space:pre"> </span>; ps !<br>nsteps <span class="Apple-tab-span" style="white-space:pre"> </span> = 2500000<span class="Apple-tab-span" style="white-space:pre"> </span>; total 5ns.<br><br>; OPTIONS FOR BONDS<br>; Constrain control<br>constraints<span class="Apple-tab-span" style="white-space:pre"> </span> = all-bonds<br>; Do not constrain the start configuration<br>continuation = no<br>; Type of constraint algorithm<br>constraint-algorithm = lincs<br><br>; OUTPUT CONTROL OPTIONS<br>; Output frequency for coords (x), velocities (v) and forces (f)<br>nstxout = 100000<br>nstvout <span class="Apple-tab-span" style="white-space:pre"> </span> = 100000<br>nstfout <span class="Apple-tab-span" style="white-space:pre"> </span> = 100000<br>; Output frequency and precision for xtc file<br>nstxtcout <span class="Apple-tab-span" style="white-space:pre"> </span> = 5000<br>xtc-precision <span class="Apple-tab-span" style="white-space:pre"> </span> = 1000<br>; Energy monitoring<br>energygrps <span class="Apple-tab-span" style="white-space:pre"> </span> = Protein<span class="Apple-tab-span" style="white-space:pre"> </span>Non-Protein<br>nstenergy<span class="Apple-tab-span" style="white-space:pre"> </span> = 1000<br><br>; NEIGHBORSEARCHING PARAMETERS<br>; nblist update frequency<br>nstlist <span class="Apple-tab-span" style="white-space:pre"> </span> = 5 <br>; ns algorithm (simple or grid)<br>ns-type <span class="Apple-tab-span" style="white-space:pre"> </span> = Grid<br>; nblist cut-off <br>rlist <span class="Apple-tab-span" style="white-space:pre"> </span> = 0.8<br><br>; OPTIONS FOR ELECTROSTATICS AND VDW<br>; Method for doing electrostatics<br>coulombtype = Reaction-Field <br>rcoulomb <span class="Apple-tab-span" style="white-space:pre"> </span> = 1.4 <br>epsilon_rf<span class="Apple-tab-span" style="white-space:pre"> </span> = 62 ; As suggested at J Comput Chem. 2004 Oct;25(13):1656-76.<br>vdw-type = Cut-off<br>; cut-off lengths <br>rvdw = 1.4<br>; Apply long range dispersion corrections for Energy and Pressure<br>DispCorr = no<br><br>; OPTIONS FOR WEAK COUPLING ALGORITHMS<br>; Temperature coupling <br>tcoupl = berendsen<br>; Groups to couple separately, time constant (ps) and reference temperature (K)<br>tc-grps = Protein<span class="Apple-tab-span" style="white-space:pre"> </span>Non-Protein<br>tau-t = 0.1<span class="Apple-tab-span" style="white-space:pre"> </span>0.1<span class="Apple-tab-span" style="white-space:pre"> </span> <br>ref-t = 300<span class="Apple-tab-span" style="white-space:pre"> </span>300<br>; Pressure coupling <br>Pcoupl = berendsen<br>Pcoupltype = isotropic<br>; Time constant (ps), compressibility (1/bar) and reference P (bar)<br>tau_p = 1.0<span class="Apple-tab-span" style="white-space:pre"> </span><br>compressibility <span class="Apple-tab-span" style="white-space:pre"> </span> = 4.5e-5 <br>ref_p <span class="Apple-tab-span" style="white-space:pre"> </span> = 1.0 <br>; Generate velocites is on at 290K - do not get velocity from gro file.<br>gen_vel = yes<br>gen_temp = 290<br>gen-seed = -1<br><br>; Center of mass control<br>nstcomm = 10000<br>; Periodic boundary conditions <br>pbc = xyz<br>; Mode for center of mass motion removal<br>comm-mode = Linear<br>; Groups for center of mass motion removal<br>comm-grps = system</font><br><br></div><div>The error message we got are LINCS related, eg:</div><div><div><font class="Apple-style-span" face="'Courier New'">Step 40941, time 40.941 (ps) LINCS WARNING</font></div><div><font class="Apple-style-span" face="'Courier New'">relative constraint deviation after LINCS:</font></div><div><font class="Apple-style-span" face="'Courier New'">rms 0.000021, max 0.000112 (between atoms 981 and 982)</font></div><div><font class="Apple-style-span" face="'Courier New'">bonds that rotated more than 30 degrees:</font></div><div><font class="Apple-style-span" face="'Courier New'"> atom 1 atom 2 angle previous, current, constraint length</font></div><div><font class="Apple-style-span" face="'Courier New'"> 981 982 34.0 0.0998 0.1000 0.1000</font></div><div><font class="Apple-style-span" face="'Courier New'"><br></font></div><div><font class="Apple-style-span" face="'Courier New'">Step 40942, time 40.942 (ps) LINCS WARNING</font></div><div><font class="Apple-style-span" face="'Courier New'">relative constraint deviation after LINCS:</font></div><div><font class="Apple-style-span" face="'Courier New'">rms 0.000140, max 0.001170 (between atoms 981 and 982)</font></div><div><font class="Apple-style-span" face="'Courier New'">bonds that rotated more than 30 degrees:</font></div><div><font class="Apple-style-span" face="'Courier New'"> atom 1 atom 2 angle previous, current, constraint length</font></div><div><font class="Apple-style-span" face="'Courier New'"> 981 982 31.7 0.1000 0.1001 0.1000</font></div><div><font class="Apple-style-span" face="'Courier New'"><br></font></div><div><font class="Apple-style-span" face="'Courier New'">Step 40943, time 40.943 (ps) LINCS WARNING</font></div><div><font class="Apple-style-span" face="'Courier New'">relative constraint deviation after LINCS:</font></div><div><font class="Apple-style-span" face="'Courier New'">rms 0.000106, max 0.000860 (between atoms 981 and 982)</font></div><div><font class="Apple-style-span" face="'Courier New'">bonds that rotated more than 30 degrees:</font></div><div><font class="Apple-style-span" face="'Courier New'"> atom 1 atom 2 angle previous, current, constraint length</font></div><div><font class="Apple-style-span" face="'Courier New'"> 981 982 30.2 0.1001 0.1001 0.1000</font></div><div><font class="Apple-style-span" face="'Courier New'"><br></font></div><div><font class="Apple-style-span" face="'Courier New'">Step 40944, time 40.944 (ps) LINCS WARNING</font></div><div><font class="Apple-style-span" face="'Courier New'">relative constraint deviation after LINCS:</font></div><div><font class="Apple-style-span" face="'Courier New'">rms 0.000053, max 0.000571 (between atoms 979 and 981)</font></div><div><font class="Apple-style-span" face="'Courier New'">bonds that rotated more than 30 degrees:</font></div><div><font class="Apple-style-span" face="'Courier New'"> atom 1 atom 2 angle previous, current, constraint length</font></div><div><font class="Apple-style-span" face="'Courier New'"> 981 982 35.2 0.1001 0.1000 0.1000</font></div><div><font class="Apple-style-span" face="'Courier New'"><br></font></div><div><font class="Apple-style-span" face="'Courier New'">Step 40945, time 40.945 (ps) LINCS WARNING</font></div><div><font class="Apple-style-span" face="'Courier New'">relative constraint deviation after LINCS:</font></div><div><font class="Apple-style-span" face="'Courier New'">rms 0.000225, max 0.001915 (between atoms 981 and 982)</font></div><div><font class="Apple-style-span" face="'Courier New'">bonds that rotated more than 30 degrees:</font></div><div><font class="Apple-style-span" face="'Courier New'"> atom 1 atom 2 angle previous, current, constraint length</font></div><div><font class="Apple-style-span" face="'Courier New'"> 981 982 36.4 0.1000 0.0998 0.1000</font></div><div><font class="Apple-style-span" face="'Courier New'"><br></font></div><div><font class="Apple-style-span" face="'Courier New'">-------------------------------------------------------</font></div><div><font class="Apple-style-span" face="'Courier New'">Program mdrun_mpi_bg, VERSION 4.5.4</font></div><div><font class="Apple-style-span" face="'Courier New'">Source code file: ../../../gromacs-4.5.4/src/mdlib/constr.c, line: 176</font></div><div><font class="Apple-style-span" face="'Courier New'"><br></font></div><div><font class="Apple-style-span" face="'Courier New'">Fatal error:</font></div><div><font class="Apple-style-span" face="'Courier New'">Too many LINCS warnings (1000)</font></div><div><font class="Apple-style-span" face="'Courier New'">If you know what you are doing you can adjust the lincs warning threshold in your mdp file</font></div><div><font class="Apple-style-span" face="'Courier New'">or set the environment variable GMX_MAXCONSTRWARN to -1,</font></div><div><font class="Apple-style-span" face="'Courier New'">but normally it is better to fix the problem</font></div><div><font class="Apple-style-span" face="'Courier New'">For more information and tips for troubleshooting, please check the GROMACS</font></div><div><font class="Apple-style-span" face="'Courier New'">website at <a href="http://www.gromacs.org/Documentation/Errors">http://www.gromacs.org/Documentation/Errors</a></font></div><div><font class="Apple-style-span" face="'Courier New'">-------------------------------------------------------</font></div><div><br></div></div><div> Now, I think that there is some problem with gromacs 4.5.4 because the <b>same</b> system, using the <b>same</b> run parameter was successfully simulated using 4.0.7. I used GROMOS53a6 with SPC water whenever running this protein. The only difference between a crash and a successful run was gromacs version.</div><br><blockquote type="cite"><div>I'd also add that we need a detailed description of the system, including force field used and any other special considerations (distance restraints, modified parameters, etc). An .mdp file would also be useful for the run that crashes.<br></div></blockquote><div><br></div><div>The only constraints I had in the system LINCS of all bonds. I didn't modified the FF in anyway.</div><div><br></div><div>Best,</div><div>Itamar</div><br><blockquote type="cite"><div><br>-Justin<br><br><blockquote type="cite">Do this for 4.0.7 and 4.5.4, for which I trust that you have been using exactly identical test systems. If not, then please try it again while conserving the system.<br></blockquote><blockquote type="cite">Chris.<br></blockquote><blockquote type="cite">-- original message --<br></blockquote><blockquote type="cite">Hi Matthew,<br></blockquote><blockquote type="cite">Thanks for the reply. First, I don't thinks it is poorly compiled bin, as I<br></blockquote><blockquote type="cite">used both GROMACS compiled by me (on my machine) or by the sys-admin on<br></blockquote><blockquote type="cite">Linux cluster or blue-gene.<br></blockquote><blockquote type="cite">The simulations using 4.5.4 crashed giving LINCS error, which is not the<br></blockquote><blockquote type="cite">case with 4.0.7 (using the same mdp and pdb files). Second, I don't thinks<br></blockquote><blockquote type="cite">it is poorly compiled bin, as I used both GROMACS compiled with me (on my<br></blockquote><blockquote type="cite">machine) or by the sys-admin on Linux cluster/blue-gene.<br></blockquote><blockquote type="cite">cheers,<br></blockquote><blockquote type="cite">Itamar<br></blockquote><blockquote type="cite">On 18 August 2011 01:48, Matthew Zwier <mczwier at <a href="http://gmail.com">gmail.com</a>> wrote:<br></blockquote><blockquote type="cite"><blockquote type="cite">Could be a system blowing up, or perhaps a mis-compiled binary. What<br></blockquote></blockquote><blockquote type="cite"><blockquote type="cite">error messages do you get when the crash occurs?<br></blockquote></blockquote><blockquote type="cite"><blockquote type="cite"><br></blockquote></blockquote><blockquote type="cite"><blockquote type="cite">On Tue, Aug 16, 2011 at 9:48 PM, Itamar Kass <itamar.kass at <a href="http://monash.edu">monash.edu</a>><br></blockquote></blockquote><blockquote type="cite"><blockquote type="cite">wrote:<br></blockquote></blockquote><blockquote type="cite"><blockquote type="cite">> Hi all GROMACS useres and developers,<br></blockquote></blockquote><blockquote type="cite"><blockquote type="cite">><br></blockquote></blockquote><blockquote type="cite"><blockquote type="cite">> I am interesting in simulating a small protein (~140 aa) in water, with<br></blockquote></blockquote><blockquote type="cite"><blockquote type="cite">and without Ca ions. In order to do so, I had used version 4.5.4. I had<br></blockquote></blockquote><blockquote type="cite"><blockquote type="cite">solvate the protein in water, add ions to naturalise the systems,<br></blockquote></blockquote><blockquote type="cite"><blockquote type="cite">equilibrated the systems and then tried productive runs. Now, no matter what<br></blockquote></blockquote><blockquote type="cite"><blockquote type="cite">I did, it crashed after few ps's of free MD or during the PR runs.<br></blockquote></blockquote><blockquote type="cite"><blockquote type="cite">><br></blockquote></blockquote><blockquote type="cite"><blockquote type="cite">> Few of the things I had tried are:<br></blockquote></blockquote><blockquote type="cite"><blockquote type="cite">> 1. Running the simulations on different systems (OSX, linux or<br></blockquote></blockquote><blockquote type="cite"><blockquote type="cite">blue-gene).<br></blockquote></blockquote><blockquote type="cite"><blockquote type="cite">> 2. Using single or double precision versions.<br></blockquote></blockquote><blockquote type="cite"><blockquote type="cite">> 3. An equilibration stage, 1ns long with a time-step of 1fs, during which<br></blockquote></blockquote><blockquote type="cite"><blockquote type="cite">the restrained forces where gradually reduced from 1000 to 50 kJ mol-1 nm-2.<br></blockquote></blockquote><blockquote type="cite"><blockquote type="cite">> 4. Running part of the equilibration stage as NVT and then switched to<br></blockquote></blockquote><blockquote type="cite"><blockquote type="cite">NPT.<br></blockquote></blockquote><blockquote type="cite"><blockquote type="cite">> 5. Started from different x-ray structures, with resolutions differ from<br></blockquote></blockquote><blockquote type="cite"><blockquote type="cite">2.5 to 1.7 Angstrom.<br></blockquote></blockquote><blockquote type="cite"><blockquote type="cite">><br></blockquote></blockquote><blockquote type="cite"><blockquote type="cite">> Finally I had moved back to 4.0.7 which worked like charm. I wonder if<br></blockquote></blockquote><blockquote type="cite"><blockquote type="cite">someone else had encounter something like this. Attached please find the mdp<br></blockquote></blockquote><blockquote type="cite"><blockquote type="cite">files I used.<br></blockquote></blockquote><blockquote type="cite"><blockquote type="cite">><br></blockquote></blockquote><blockquote type="cite"><blockquote type="cite">> All the best,<br></blockquote></blockquote><blockquote type="cite"><blockquote type="cite">> Itamar.<br></blockquote></blockquote><blockquote type="cite"><blockquote type="cite">><br></blockquote></blockquote><blockquote type="cite"><blockquote type="cite">><br></blockquote></blockquote><blockquote type="cite"><blockquote type="cite">><br></blockquote></blockquote><blockquote type="cite"><blockquote type="cite">><br></blockquote></blockquote><br>-- <br>========================================<br><br>Justin A. Lemkul<br>Ph.D. Candidate<br>ICTAS Doctoral Scholar<br>MILES-IGERT Trainee<br>Department of Biochemistry<br>Virginia Tech<br>Blacksburg, VA<br>jalemkul[at]vt.edu | (540) 231-9080<br><a href="http://www.bevanlab.biochem.vt.edu/Pages/Personal/justin">http://www.bevanlab.biochem.vt.edu/Pages/Personal/justin</a><br><br>========================================<br>-- <br>gmx-users mailing list gmx-users@gromacs.org<br>http://lists.gromacs.org/mailman/listinfo/gmx-users<br>Please search the archive at http://www.gromacs.org/Support/Mailing_Lists/Search before posting!<br>Please don't post (un)subscribe requests to the list. Use the www interface or send it to gmx-users-request@gromacs.org.<br>Can't post? Read http://www.gromacs.org/Support/Mailing_Lists<br></div></blockquote></div><br><div apple-content-edited="true">-----<br>"In theory, there is no difference between theory and practice. But, in practice, there is." - Jan L.A. van de Snepscheut<br><br>===========================================<br>| Itamar Kass, Ph.D.<br>| Postdoctoral Research Fellow<br>|<br>| Department of Biochemistry and Molecular Biology<br>| Building 77 Clayton Campus<br>| Wellington Road<br>| Monash University,<br>| Victoria 3800<br>| Australia<br>|<br>| Tel: +61 3 9902 9376<br>| Fax: +61 3 9902 9500<br>| E-mail: <a href="mailto:Itamar.Kass@monash.edu">Itamar.Kass@monash.edu</a><br>============================================<br></div><br></div></body></html>