<html><head><meta http-equiv=Content-Type content="text/html; charset=iso-8859-1"><META name="Author" content="Novell GroupWise WebAccess"></head><body style='font-family: Tahoma, sans-serif; font-size: 13px; '>At first I would like to say that I deeply apologize for <br>the cave-like things I have said. I again say, that this<br>was not the field I am deeply involved.<br>From Gerrit I got a banana.<br>For this guy, I am a cave-man.<br><br>Thanks, for being such ready for open discussion. <br><br>I did not tell that I do not want to be wrong.<br>Questions, which are included in my doubts: <br><br>Generalized forces and averages for H+ interchange ?<br>Comparison with titration experiments ?<br>Is there any experimental evidence for the rates of<br>interchange ?<br>Are simulation-times or the periods of interchange at <br>any time realistic?<br>Are equilibria sampled well, with such interchanges,<br>or are there jumps in free energy by this interchange ?<br>Why is there no free H+ ?<br><br>Thanks for your kind and very constructive criticisms.<br><br>I would appreciate, if this so-called discussion will <br>find an end.<br>I am deeply depressed about such comments and<br>I will not take part in any users-discussion in the future.<br>It makes no sense, because talking like this expresses<br>the way on how science is done today. Repelling that<br>person, who does not walk the common way.<br>And:<br><br>Maybe I have lived in a cave, but someone like you, who answers in <br>such a way, IS A CAVEMAN !<br><br>>>> Joćo Henriques<joao.henriques.32353@gmail.com> 07.09.11 11.30 Uhr >>><br>There is no problem in being wrong. The problem is that he wants to be<br>wrong. At least 4 different researchers gave constructive input and<br>this subject keeps hitting the same key. I've always been told that<br>worse than not knowing, is not wanting to know.<br><br>Still, I apologize for my outburst.<br><br>Best regards,<br><br>On Wed, Sep 7, 2011 at 1:54 AM, Mark Abraham <Mark.Abraham@anu.edu.au> wrote:<br>> On 7/09/2011 3:53 AM, Joćo Henriques wrote:<br>>><br>>> I guess someone has been living in a cave for the past decade or so...<br>><br>> Please keep contributions to the mailing list constructive :-) Everyone's<br>> been wrong before!<br>><br>> Mark<br>> --<br>> gmx-users mailing list gmx-users@gromacs.org<br>> http://lists.gromacs.org/mailman/listinfo/gmx-users<br>> Please search the archive at<br>> http://www.gromacs.org/Support/Mailing_Lists/Search before posting!<br>> Please don't post (un)subscribe requests to the list. Use the www interface<br>> or send it to gmx-users-request@gromacs.org.<br>> Can't post? Read http://www.gromacs.org/Support/Mailing_Lists<br>><br><br><br><br>-- <br>Joćo Henriques<br>--<br>gmx-users mailing list gmx-users@gromacs.org<br>http://lists.gromacs.org/mailman/listinfo/gmx-users<br>Please search the archive at http://www.gromacs.org/Support/Mailing_Lists/Search before posting!<br>Please don't post (un)subscribe requests to the list. Use the<br>www interface or send it to gmx-users-request@gromacs.org.<br>Can't post? Read http://www.gromacs.org/Support/Mailing_Lists<br></body></html>