<html><body><div style="color:#000; background-color:#fff; font-family:times new roman, new york, times, serif;font-size:12pt"><div>Dear All,</div><div> </div><div>Some of the complexes of PDB files in RCSB are not from protein-protein interaction, but from the packing of protein crystal. Thus in solution the "protien complex" may dissociate.</div><div> </div><div>However as for the protein are usually very large, and I regard it is difficult to observe that 2 (or more) subunit protein complex dissociate completely during MD simulation.</div><div> </div><div>Can you please introduce to me your experience that the "protein complex" sifnificantly dissociate during MD<var id="yui-ie-cursor"></var>?</div><div> </div><div>I am looking forward to getting your reply.</div><div> </div><div>Cheers,</div><div> </div><div>Dialing</div><div> </div></div></body></html>