
<html dir="ltr">

<head>

<meta http-equiv="Content-Type" content="text/html; charset=iso-8859-1">

<style type="text/css" id="owaParaStyle"></style><style type="text/css" style="">

<!--

-->

</style><style type="text/css" style="">

<!--

-->

</style><style type="text/css" style="display: none !important;">object:not([type]),object[classid$=":D27CDB6E-AE6D-11cf-96B8-444553540000"],object[classid$=":d27cdb6e-ae6d-11cf-96b8-444553540000"],object[codebase*="swflash.cab"],object[data*=".swf"],embed[type="application/x-shockwave-flash"],embed[src*=".swf"],object[type="application/x-shockwave-flash"],object[src*=".swf"],object[codetype="application/x-shockwave-flash"],iframe[type="application/x-shockwave-flash"],object[classid$=":166B1BCA-3F9C-11CF-8075-444553540000"],object[codebase*="sw.cab"],object[data*=".dcr"],embed[type="application/x-director"],embed[src*=".dcr"],object[type="application/x-director"],object[src*=".dcr"],object[classid$=":15B782AF-55D8-11D1-B477-006097098764"],object[codebase*="awswaxf.cab"],object[data*=".aam"],embed[type="application/x-authorware-map"],embed[src*=".aam"],object[type="application/x-authorware-map"],object[src*=".aam"],object[classid*="32C73088-76AE-40F7-AC40-81F62CB2C1DA"],object[type="application/ag-plugin"],object[type="application/x-silverlight"],object[type="application/x-silverlight-2"],object[source*=".xaml"],object[sourceelement*="xaml"],embed[type="application/ag-plugin"],embed[source*=".xaml"]{display: none !important;}</style><style type="text/css" style="display: none !important;">object:not([type]),object[classid$=":D27CDB6E-AE6D-11cf-96B8-444553540000"],object[classid$=":d27cdb6e-ae6d-11cf-96b8-444553540000"],object[codebase*="swflash.cab"],object[data*=".swf"],embed[type="application/x-shockwave-flash"],embed[src*=".swf"],object[type="application/x-shockwave-flash"],object[src*=".swf"],object[codetype="application/x-shockwave-flash"],iframe[type="application/x-shockwave-flash"],object[classid$=":166B1BCA-3F9C-11CF-8075-444553540000"],object[codebase*="sw.cab"],object[data*=".dcr"],embed[type="application/x-director"],embed[src*=".dcr"],object[type="application/x-director"],object[src*=".dcr"],object[classid$=":15B782AF-55D8-11D1-B477-006097098764"],object[codebase*="awswaxf.cab"],object[data*=".aam"],embed[type="application/x-authorware-map"],embed[src*=".aam"],object[type="application/x-authorware-map"],object[src*=".aam"],object[classid*="32C73088-76AE-40F7-AC40-81F62CB2C1DA"],object[type="application/ag-plugin"],object[type="application/x-silverlight"],object[type="application/x-silverlight-2"],object[source*=".xaml"],object[sourceelement*="xaml"],embed[type="application/ag-plugin"],embed[source*=".xaml"]{display: none !important;}</style>

</head>

<body fpstyle="1" ocsi="0">

<div style="direction: ltr;font-family: Tahoma;color: #000000;font-size: 10pt;">

<div style="font-family: Times New Roman; color: #000000; font-size: 16px">

<div id="divRpF570115" style="direction: ltr; "><br>

</div>

<div></div>

<div>

<div style="direction:ltr; font-family:Tahoma; color:#000000; font-size:10pt">

<div><span style="font-family:monospace; font-size:16px">Dear gmx user</span></div>

<span style="font-family:monospace; font-size:16px">

<div><span style="font-family:monospace; font-size:16px"><br>

</span></div>

If I may I have a specific question about replica exchange.</span><br style="font-family:monospace; font-size:16px">

<span style="font-family:monospace; font-size:16px">I want to define different Hamiltonians for the different temperatures.</span><br style="font-family:monospace; font-size:16px">

<span style="font-family:monospace; font-size:16px">It seems that the replica exchange can handle it. I wanted to ask if it's implemented in a general way so different Hamiltonians can be used for different temperatures?</span><br style="font-family:monospace; font-size:16px">

<br style="font-family:monospace; font-size:16px">

<span style="font-family:monospace; font-size:16px">Thanks a lot,</span><br style="font-family:monospace; font-size:16px">

<span style="font-family:monospace; font-size:16px">Best regards,</span><br style="font-family:monospace; font-size:16px">

<span style="font-family:monospace; font-size:16px">Asaf</span> </div>

</div>

</div>

</div>

</body>

</html>